Resumen Los inhibidores del punto de control inmunitario han demostrado mejorar el pronóstico de múltiples enfer medades oncológicas. Recientemente se han reportado eventos adversos relacionados a la inmunoterapia. La to xicidad neurológica es poco frecuente. Se presenta el caso de un paciente con encefalitis relacionada con inhibido res del punto de control inmunitario.

Abstract Immune checkpoint inhibitors have been shown to improve the prognosis of multiple oncological diseases. Recently, adverse events related to immunotherapy have been reported. Neurologic toxicity is infrequent. We pre sent the case of a patient with encephalitis associated to immune checkpoint inhibitors.

Objetivou-se analisar a atuação do Conselho Nacional de Saúde no núcleo do processo decisório da política de saúde entre 2014-2017. A análise foi baseada nos projetos políticos em disputa na arena política da saúde e nos projetos dos governos de Dilma e de Temer. Com a mudança no projeto de governo, o Conselho passou a atuar pela via judicial, além de pelas vias social e parlamentar, passando do alinhamento (crítico) à franca oposição, até sua neutralização com o boicote da participação do Conselho nas discussões de pautas da política de saúde nos anos 2016-2017. Embora não tenha tido poder suficiente para mudar a correlação de forças em torno do desmonte do Sistema Único de Saúde (SUS), o Conselho figurou-se em um bloco político de resistência e de enfrentamento em defesa do SUS constitucional.

This study aimed to analyze the role of the National Health Council in the core of the decision-making process of health policy in the period 2014-2017. The analysis was based on the political disputed projects in the health policy sphere and on the government projects of former Presidents Dilma Rousseff and Michel Temer. Due to the government’s project change, in addition to the social and parliamentary channels, the Council started to act through the judicial channel as well, moving from critical alignment to outright opposition until its neutralization, with the Council’s participation boycott in the health policy agenda discussions in the period 2016-2017. Although it did not have enough power to change the balance of forces surrounding the deconstruction of the Brazilian National Health System (SUS), the Council was part of a political bloc of resistance and confrontation in defense of the constitutional SUS.

El objetivo fue el análisis de la actuación del Consejo Nacional de Salud en el núcleo del proceso de decisión de la política de salud entre 2014-2017. El análisis tuvo como base los proyectos políticos en disputa en la arena política de la salud y en los proyectos de los gobiernos Dilma y Temer. Con el cambio en el proyecto de gobierno, el Consejo pasó a actuar, además de en las vías social y parlamentaria, en la vía judicial, pasando del alineamiento (crítico) a la franca oposición, hasta su neutralización, con el boicot de la participación del Consejo en las discusiones de pautas de la política de salud en los años 2016-2017. Aunque no haya tenido poder suficiente para cambiar la correlación de fuerzas alrededor del desmontaje del Sistema Brasileño de Salud (SUS), el Consejo se configuró como un bloque político de resistencia y de enfrentamiento, en defensa del SUS constitucional.

Objetivou-se analisar a atuação do Conselho Nacional de Saúde no núcleo do processo decisório da política de saúde entre 2014-2017. A análise foi baseada nos projetos políticos em disputa na arena política da saúde e nos projetos dos governos de Dilma e de Temer. Com a mudança no projeto de governo, o Conselho passou a atuar pela via judicial, além de pelas vias social e parlamentar, passando do alinhamento (crítico) à franca oposição, até sua neutralização com o boicote da participação do Conselho nas discussões de pautas da política de saúde nos anos 2016-2017. Embora não tenha tido poder suficiente para mudar a correlação de forças em torno do desmonte do Sistema Único de Saúde (SUS), o Conselho figurou-se em um bloco político de resistência e de enfrentamento em defesa do SUS constitucional.

This study aimed to analyze the role of the National Health Council in the core of the decision-making process of health policy in the period 2014-2017. The analysis was based on the political disputed projects in the health policy sphere and on the government projects of former Presidents Dilma Rousseff and Michel Temer. Due to the government’s project change, in addition to the social and parliamentary channels, the Council started to act through the judicial channel as well, moving from critical alignment to outright opposition until its neutralization, with the Council’s participation boycott in the health policy agenda discussions in the period 2016-2017. Although it did not have enough power to change the balance of forces surrounding the deconstruction of the Brazilian National Health System (SUS), the Council was part of a political bloc of resistance and confrontation in defense of the constitutional SUS.

El objetivo fue el análisis de la actuación del Consejo Nacional de Salud en el núcleo del proceso de decisión de la política de salud entre 2014-2017. El análisis tuvo como base los proyectos políticos en disputa en la arena política de la salud y en los proyectos de los gobiernos Dilma y Temer. Con el cambio en el proyecto de gobierno, el Consejo pasó a actuar, además de en las vías social y parlamentaria, en la vía judicial, pasando del alineamiento (crítico) a la franca oposición, hasta su neutralización, con el boicot de la participación del Consejo en las discusiones de pautas de la política de salud en los años 2016-2017. Aunque no haya tenido poder suficiente para cambiar la correlación de fuerzas alrededor del desmontaje del Sistema Brasileño de Salud (SUS), el Consejo se configuró como un bloque político de resistencia y de enfrentamiento, en defensa del SUS constitucional.

Abstract The atypical clinical features in multiple sclerosis (MS) have been rarely reported and suggest the possibility of an alternative diagnosis. The aim was to describe the clinical and demographic characteristics of MS patients who debuted with atypical symptoms and to estimate the sensitivity, specificity and positive predictive value (PPV) for MS diagnosis. A retrospective analysis of clinical records was performed. The following data were recorded: patients with MS diagnosis according to current diagnostic criteria at the time of diagnosis, type of symptom at the onset, time to second relapse, presence of oligoclonal bands (OCB) in cerebrospinal fluid (CSF) and radiological red flags on MRI. A descriptive and inferential analysis was performed using the chi square test, and sensitivity, specificity and PPV were calculated. Six hundred two patients were diagnosed with MS, of which 22 (3.65%) had an atypical clinical presentation. 54.5% were women. The mean age was 29 years (SD ± 11.7). The most common atypical symptom was peripheral facial palsy (27%). The PPV for atypical onset was 6.14%; p < 0.001. Sensitivity and specificity of these symptoms to MS diagnosis were 3.65% and 19%, respectively. In our research, the presence of atypical symptoms at the onset of MS was very low. Other diseases must be excluded, taking into account their low sensitivity, specificity and PPV.

Resumen Las manifestaciones clínicas atípicas al inicio de la esclerosis múltiple (EM) son poco frecuentes y sugieren la posibilidad de un diagnóstico alternativo. El objetivo fue describir las características clínicas en la EM con síntomas atípicos al inicio, y estimar la sensibilidad, especificidad y valor predictivo posi tivo (VPP) para el diagnóstico de EM. Se trata de un análisis retrospectivo de historias clínicas. Se registraron los siguientes datos: pacientes con diagnóstico de EM acorde a los criterios diagnósticos correspondientes, tipo de síntoma de inicio, tiempo hasta la segunda recaída, presencia de bandas oligoclonales en el líquido cefalorraquídeo (LCR) y de banderas rojas radiológicas en la Resonancia Magnética de encéfalo (RMN). Se realizó un análisis descriptivo e inferencial utilizando la prueba de chi cuadrado y se calcularon la sensibilidad, la especificidad y el VPP. Seiscientos dos pacientes tuvieron un diagnóstico final de EM, de los cuales 22 (3.7%) tuvieron una presentación clínica atípica. El 54.5% eran mujeres. La edad promedio fue de 29 años (DE ± 11.7). El síntoma atípico más frecuente fue parálisis facial periférica aislada (6/22). El VPP para el inicio atípico fue de 6.1%; p < 0001. La sensibilidad y especificidad de estos síntomas al diagnóstico de EM fueron del 3.7% y 19%, respectivamente. En nuestra cohorte, demostramos que la presencia de síntomas atípicos como presentación de la EM es poco frecuente. Es mandatorio la exclusión de otras enfermedades, teniendo en cuenta su baja sensibilidad, especificidad y VPP.

Resumo O objetivo desse artigo consiste em identificar as correntes de pensamento utilizadas para a produção científica sobre conselhos e conferências de saúde, no período de 1990 a 2017. Trata-se de uma revisão integrativa de literatura realizada nas bases SciELO, LILACS e portal de periódicos da CAPES que resultou na seleção de 152 trabalhos. Estes foram analisados segundo ano de publicação, procedência institucional dos autores, veículo de divulgação, objeto e tipo de estudo e abordagem teórica. Identificou-se um aumento gradativo no número de publicações ao longo do período estudado, sendo que a maioria dos estudos com base empírica (92,8%) não explicita, nominalmente, a utilização de qualquer abordagem teórica na análise dos dados. As abordagens estruturalista, pós-estruturalista e neo-institucionalista utilizadas foram mediadas por modelo teórico, teorias de médio alcance e conceitos de autores da tradição européia, norte-americana e latino-americana. O conhecimento produzido sobre conselho e conferência de saúde no Brasil pode se beneficiar ainda mais da densidade das abordagens teóricas das ciências sociais e políticas.

Abstract This paper aimed to identify the thinking currents used for scientific production on health councils and conferences, from 1990 to 2017. This is an integrative review of literature carried out at the SciELO, LILACS and CAPES journals portals that resulted in the selection of 152 papers. They were analyzed by year of publication, author’s institutional origin, dissemination media, object and type of study and theoretical approach. We identified that a gradual increase occurred in the number of publications over the study period and most empirical studies (92.8%) do not explicitly state the use of any theoretical approach in data analysis. The structuralist, post-structuralist and neo-institutionalist approaches used were mediated by a theoretical model, medium-range theories and concepts of authors of the European, North American and Latin American traditions. The knowledge produced about health council and conference in Brazil may benefit even more from the density of theoretical approaches to social and political sciences.

Resumo O objetivo desse artigo consiste em identificar as correntes de pensamento utilizadas para a produção científica sobre conselhos e conferências de saúde, no período de 1990 a 2017. Trata-se de uma revisão integrativa de literatura realizada nas bases SciELO, LILACS e portal de periódicos da CAPES que resultou na seleção de 152 trabalhos. Estes foram analisados segundo ano de publicação, procedência institucional dos autores, veículo de divulgação, objeto e tipo de estudo e abordagem teórica. Identificou-se um aumento gradativo no número de publicações ao longo do período estudado, sendo que a maioria dos estudos com base empírica (92,8%) não explicita, nominalmente, a utilização de qualquer abordagem teórica na análise dos dados. As abordagens estruturalista, pós-estruturalista e neo-institucionalista utilizadas foram mediadas por modelo teórico, teorias de médio alcance e conceitos de autores da tradição européia, norte-americana e latino-americana. O conhecimento produzido sobre conselho e conferência de saúde no Brasil pode se beneficiar ainda mais da densidade das abordagens teóricas das ciências sociais e políticas.

Abstract This paper aimed to identify the thinking currents used for scientific production on health councils and conferences, from 1990 to 2017. This is an integrative review of literature carried out at the SciELO, LILACS and CAPES journals portals that resulted in the selection of 152 papers. They were analyzed by year of publication, author’s institutional origin, dissemination media, object and type of study and theoretical approach. We identified that a gradual increase occurred in the number of publications over the study period and most empirical studies (92.8%) do not explicitly state the use of any theoretical approach in data analysis. The structuralist, post-structuralist and neo-institutionalist approaches used were mediated by a theoretical model, medium-range theories and concepts of authors of the European, North American and Latin American traditions. The knowledge produced about health council and conference in Brazil may benefit even more from the density of theoretical approaches to social and political sciences.

Abstract: A randomized controlled parallel clinical trial was conducted to evaluate the efficacy of the association of 1.23% topical professional acidulated phosphate fluoride (APF) gel with oral hygiene and dietary instructions on the arrest of active non-cavitated lesions in permanent, mixed, and temporary dentition in children between 3 and 12 years of age. Ninety-eight caries-active children were randomly divided into two groups: a fluoride gel group (n = 49) and a non-fluoridated gel group (n = 49). Each group received up to eight weekly applications of gel, weekly professional toothbrushing with oral hygiene instructions and dietary counselling. Caries lesions were assessed qualitatively through visual-tactile criteria performed in three stages: initial, intermediate, and final. Regression models were applied to identify risk indicators for caries control. Between-group comparison regarding the time taken to arrest the lesions was performed using Chi-squared and Fisher's exact tests. Seventeen children did not receive the allocated intervention, and one was lost to follow-up (n = 80). There was no difference between the control and placebo groups regarding the time to the arrest of the lesion (p >.05). The treatments showed similar results without significant statistical difference (p = 0.33; 95%CI: 0.32–1.48). No adverse effects were observed. It can be concluded that no additional effect of the association of 1.23% APF gel with oral hygiene using fluoride dentifrice and dietary instructions on the arrest of active non-cavitated lesions could be established. We can also confirm the importance of toothbrushing frequency and, consequently, the visible plaque reduction in the control of caries activity. RBR-37V5S3

Resumen: Objetivo: Este estudio tiene como objetivo describir la producción de conocimientos de enfermería sobre el cuidado de la salud para la población indígena brasileña. Método: Se realizó una revisión de alcance en LILACS, IBECS, MEDLINE, SCOPUS, SciELO, BDENF, BTDB, CAPES Journals Portal y google scholar, en enero y febrero de 2020. Se incluyeron artículos originales, tesis y disertaciones. La revisión abarcó 16 estudios publicados entre 2010 y 2018. Resultados: Del análisis, resultaron dos categorías: las acciones de enfermería en el cuidado de la población indígena brasileña y las modalidades de atención que utiliza la enfermería en el cuidado de la población indígena. Conclusión: Se concluye que los resultados de esta revisión pueden ser de utilidad para los enfermeros que laboran en el cuidado de la población indígena, quienes necesitan estar preparados y conscientes de los desafíos que conlleva trabajar con esta población.

Abstract: Objective: This study aims to describe the production of nursing knowledge about health care for the Brazilian indigenous population. Method: A scoping review was carried out in the LILACS, IBECS, MEDLINE, SCOPUS, SciELO, BDENF, BTDB, CAPES Journal Portal and google scholar databases in January and February 2020. Original articles, theses and dissertations were included. The review covered 16 studies published between 2010 and 2018. Results: The analysis resulted in two categories: nursing actions in the care of the Brazilian indigenous population and care modalities that are used by nursing in the care provided to the indigenous population. Conclusion: It is concluded that the results of this review can be useful for nurses who work in the care of the indigenous population, who need to be prepared and sensitized to the challenges that include working with this population.

Resumo: Objetivo: O presente estudo objetiva descrever a produção do conhecimento da enfermagem sobre atenção à saúde da população indígena Brasileira. Método: Realizou-se uma scoping review nas bases LILACS, IBECS, MEDLINE, SCOPUS, SciELO, BDENF, BTDB, Portal de Periódicos da CAPES e google acadêmico, em janeiro e fevereiro de 2020. Incluíram-se artigos originais, teses e dissertações. A revisão abrangeu 16 estudos publicados entre 2010 e 2018. Resultados: Da análise, resultaram duas categorias: as ações de enfermagem no cuidado a população indígena Brasileira e as modalidades assistenciais que são utilizadas pela enfermagem no cuidado a população indígena. Conclusão: Conclui-se que os resultados desta revisão podem ser úteis para os enfermeiros que atuam no cuidado a população indígena, os quais precisam estar preparados e sensibilizados para os desafios que incluem trabalhar com essa população.

Resumo O objetivo deste artigo é analisar a participação do Conselho Nacional na construção e realização da 15ª Conferência Nacional de Saúde (CNS), bem como os principais componentes desse evento, o desenho institucional, no que se refere a sua dinâmica participativa, e as propostas e diretrizes aprovadas, e relacionar esse fenômeno político à conjuntura brasileira. Este estudo de caso sobre a 15ª CNS teve como fonte de produção de dados entrevistas com 27 conselheiros nacionais e a revisão documental de atas, notícias e outras fontes do Conselho relacionadas à 15ª Conferência. O Conselho Nacional desenvolveu estratégias para politizar a elaboração das diretrizes e intensificou a participação da sociedade por meio das conferências livres. O debate em torno da saúde em 2015 envolveu milhares de pessoas no país - afinal, foram realizadas 4.706 conferências municipais, 26 estaduais, a conferência distrital e a nacional. As principais pautas da 15ª Conferência foram a defesa da democracia e o financiamento público da saúde. A 15ª CNS ainda prevaleceu com o formato burocrático. Além das inovações na forma das conferências, é necessário ampliar a permeabilidade dos tomadores de decisão à participação social e democratizar o processo de planejamento e a gestão em saúde.

Abstract This article aims to analyze the participation of the National Council in the construction and realization of the 15th National Health Conference (CNS), as well as the main components of this event, the institutional design regarding its participatory dynamics, and the approved proposals and guidelines, relating this political phenomenon to the Brazilian context. This case study on the 15th CNS had, as data sources, the interviews with 27 national counselors and the documentary review of minutes, news and other sources of the Council related to the 15th Conference. The National Council developed strategies to politicize the elaboration of guidelines and intensified society participation through free conferences. The Health debate in 2015 involved thousands of people in the country - after all, 4,706 municipal and 26 state, district and national conferences were held. The main agendas of the 15th Conference were the defense of democracy and the public financing of health. Nonetheless, the bureaucratic format still prevailed in the 15th CNS. In addition to innovations in the form of conferences, one must increase the permeability of decision-makers to social participation and democratize the health planning and management process.

Resumo O objetivo deste artigo é analisar a participação do Conselho Nacional na construção e realização da 15ª Conferência Nacional de Saúde (CNS), bem como os principais componentes desse evento, o desenho institucional, no que se refere a sua dinâmica participativa, e as propostas e diretrizes aprovadas, e relacionar esse fenômeno político à conjuntura brasileira. Este estudo de caso sobre a 15ª CNS teve como fonte de produção de dados entrevistas com 27 conselheiros nacionais e a revisão documental de atas, notícias e outras fontes do Conselho relacionadas à 15ª Conferência. O Conselho Nacional desenvolveu estratégias para politizar a elaboração das diretrizes e intensificou a participação da sociedade por meio das conferências livres. O debate em torno da saúde em 2015 envolveu milhares de pessoas no país - afinal, foram realizadas 4.706 conferências municipais, 26 estaduais, a conferência distrital e a nacional. As principais pautas da 15ª Conferência foram a defesa da democracia e o financiamento público da saúde. A 15ª CNS ainda prevaleceu com o formato burocrático. Além das inovações na forma das conferências, é necessário ampliar a permeabilidade dos tomadores de decisão à participação social e democratizar o processo de planejamento e a gestão em saúde.

Abstract This article aims to analyze the participation of the National Council in the construction and realization of the 15th National Health Conference (CNS), as well as the main components of this event, the institutional design regarding its participatory dynamics, and the approved proposals and guidelines, relating this political phenomenon to the Brazilian context. This case study on the 15th CNS had, as data sources, the interviews with 27 national counselors and the documentary review of minutes, news and other sources of the Council related to the 15th Conference. The National Council developed strategies to politicize the elaboration of guidelines and intensified society participation through free conferences. The Health debate in 2015 involved thousands of people in the country - after all, 4,706 municipal and 26 state, district and national conferences were held. The main agendas of the 15th Conference were the defense of democracy and the public financing of health. Nonetheless, the bureaucratic format still prevailed in the 15th CNS. In addition to innovations in the form of conferences, one must increase the permeability of decision-makers to social participation and democratize the health planning and management process.

Employment is a very important aspect of a person's life, and that is why any health-related factor that can interfere in such activity must be identified. The reality of a Latin American country is different and should be approached as a separate object of study. Many factors that contribute to a patient losing the job can be identified in time in order to be reversed or compensated. Thus, identifying the vulnerability profile of the patients with multiple sclerosis (MS) who are at risk of losing their jobs is an important task for researchers. Physical disability and disease course are both strong predictors of work status in MS patients, however, cognition and affective variables do not have the same degree of evidence. This study raises the aim of investigating the relationship between employment status and cognitive performance in MS. With this knowledge, it would be possible to design a neuropsychological rehabilitation plan for patients, which focuses on compensating and recovering from cognitive impairment, as well as on serving as orientation for the person who is at risk of losing their job. A group difference design was used. The sample units were selected through a non-probability accidental sampling. We collected the data of 61 patients with relapsing-remitting MS (RRMS) who had attended consultation between April 2014 and April 2015, in a public hospital. 29.5% were unemployed; 54.1% were employed; and 10.4% were students or housewives. The Brief Repeatable Battery of Neuropsychology Tests adapted for Argentine population; Symbol Digit Modalities Test (SDMT), Expanded Disability Status Scale (EDSS) and Beck Depression Inventory-II (BDI-II), were administered individually in two sessions, one with a neurologist and one with the neuropsychologist in a private consulting room. Age and years of instruction differences between patients with and without employment were not significant. There were 60.8% of patients with cognitive impairment. Among them, 38.7% were unemployed. The relationship between cognitive deterioration and work status was not significant, X² = .404, df = 1, p = .371. When comparing the groups in the cognitive battery, a meaningful difference in cognitive performance was observed between the subjects who had a job with those who were unemployed in SDMT (t = -2.421, df = 49, p = .019); performance being higher among the former. No other cognitive score showed significant results. Unemployed patients had higher EDSS and depression, than those with jobs. The cognitive tests administered, together with the BDI-II and EDSS, were included in the binary logistic regression analysis. The second model retained the SDMT and the BDI-II; both tests were ableto correctly classify almost 80% of the cases. Also, both SDMT (ß = .080, p = .014) and BDI-II (ß = -.098, p = .022) shown significant effects on work status. This study is one of the first attempts in Argentina to analyze the possible determinants of unemployment, which is extremely important in the context of a lack of determining literature about the issue in Latin America. According to results, patients with RRMS who are unemployed have worse performance in speed of information processing, more depression and physical disability than those who retain their jobs. Results are in line with previous studies, although in the present research a cognitive variable showed a greater negative influence on employment status over motor difficulties or physical disability. Clinicians would be able to identify patients whose profile shows a higher tendency towards work life decline, so that they can receive early treatment and delay that progression. It is suggested the realization of a multicentric Latin American study, blind to the patients labor status, with the aim of broadening the results by improving the study methodology.

La discapacidad física y el curso de la enfermedad son fuertes predictores del estatus laboral en los pacientes con Esclerosis Múltiple (EM). Sin embargo, la cognición no tiene el mismo grado de evidencia. Este estudio plantea el objetivo de investigar la relación entre la situación laboral y el rendimiento cognitivo en la EM. Se recogieron los datos de 61 pacientes con EM de curso recurrente-remitente (EMRR) que fueron a atenderse en un hospital público entre abril de 2014 y abril de 2015. El 29.5% estaban desempleados, el 54.1% estaban empleados y el 10.4% eran estudiantes o amas de casa. Se implementaron como test neuropsicológicos la Batería Neuropsicológica Breve para Esclerosis Múltiple y el test Símbolo-Dígito. Además se administraron la Escala de Estatus de Discapacidad Expandida y el Inventario de Depresión de Beck II. La evaluación se realizó de forma individual en dos sesiones, una con el neurólogo y otra con el neuropsicólogo en un consultorio privado. Las diferencias no fueron significativas en edad y años de instrucción entre los pacientes con y sin empleo. En cambio, los pacientes desempleados tenían un puntaje más bajo en el Símbolo-Dígito, así como la Escala de Estatus de Discapacidad Expandida y un Inventario de Depresión de Beck más altos que aquellos con trabajos. Los pacientes con EMRR que estaban desempleados tenían un peor desempeño en la velocidad de procesamiento de la información, más depresión y discapacidad física que aquellos que conservan sus trabajos.

Resumo A pesquisa consiste numa análise política das entidades integrantes do Conselho Nacional de Saúde (CNS), eleitas para o triênio 2015/2018, baseada no pensamento estratégico de Testa e nos conceitos de atores estatais e atores societais. Trata-se de um estudo de caso desenvolvido no CNS. Os dados foram produzidos a partir da análise de documentos de três origens relativas ao processo eleitoral do conselho, às suas comissões intersetoriais e às atas das reuniões entre 2014 e 2017. Ademais, foram entrevistados os conselheiros atuantes no período da pesquisa. Embora o colegiado seja formado por 144 conselheiros, tendo 48 titulares, um núcleo restrito de conselheiros concentra as principais atividades do CNS e influencia o posicionamento desta institucionalidade. A análise das disputas de poder no CNS permitiu identificar interesses relacionados à luta pelo reconhecimento, à ampliação do lucro no setor saúde e à defesa do SUS constitucional. Apesar da pluralidade de interesses, identificou-se um alinhamento político entre os fóruns em torno da defesa do SUS, buscando ampliar o poder do CNS no processo decisório da política de saúde. Esta convergência revela o quão compelido se acha o CNS dada a atual conjuntura de desmonte da seguridade social.

Abstract This is a political analysis of the institutions that are part of the National Health Council (CNS), elected for the triennium 2015/2018. This case study, developed at CNS, was based on Testa's strategic thinking and the concepts of state actors and societal actors. Data were produced from the analysis of documents from three sources related to the council’s electoral process, to its inter-sector committees and to the minutes of the 2014-2017 meetings. In addition, the advisers were interviewed during the research period. Although the board is made up of 144 counselors, with 48 full members, a restricted core of councilors concentrates CNS main activities and influences its positioning. The analysis of power disputes in the CNS allowed the identification of interests related to the struggle for recognition, the expansion of profit making in the health sector and the defense of the constitutional SUS. Despite the plurality of interests, it was identified a political alignment between the forums regarding the defense of the SUS, seeking to broaden the power of the CNS in the decision-making process of health policy. This convergence reveals how compelled the CNS is, given the current situation of social security dismantling.

Resumo A pesquisa consiste numa análise política das entidades integrantes do Conselho Nacional de Saúde (CNS), eleitas para o triênio 2015/2018, baseada no pensamento estratégico de Testa e nos conceitos de atores estatais e atores societais. Trata-se de um estudo de caso desenvolvido no CNS. Os dados foram produzidos a partir da análise de documentos de três origens relativas ao processo eleitoral do conselho, às suas comissões intersetoriais e às atas das reuniões entre 2014 e 2017. Ademais, foram entrevistados os conselheiros atuantes no período da pesquisa. Embora o colegiado seja formado por 144 conselheiros, tendo 48 titulares, um núcleo restrito de conselheiros concentra as principais atividades do CNS e influencia o posicionamento desta institucionalidade. A análise das disputas de poder no CNS permitiu identificar interesses relacionados à luta pelo reconhecimento, à ampliação do lucro no setor saúde e à defesa do SUS constitucional. Apesar da pluralidade de interesses, identificou-se um alinhamento político entre os fóruns em torno da defesa do SUS, buscando ampliar o poder do CNS no processo decisório da política de saúde. Esta convergência revela o quão compelido se acha o CNS dada a atual conjuntura de desmonte da seguridade social.

Abstract This is a political analysis of the institutions that are part of the National Health Council (CNS), elected for the triennium 2015/2018. This case study, developed at CNS, was based on Testa's strategic thinking and the concepts of state actors and societal actors. Data were produced from the analysis of documents from three sources related to the council’s electoral process, to its inter-sector committees and to the minutes of the 2014-2017 meetings. In addition, the advisers were interviewed during the research period. Although the board is made up of 144 counselors, with 48 full members, a restricted core of councilors concentrates CNS main activities and influences its positioning. The analysis of power disputes in the CNS allowed the identification of interests related to the struggle for recognition, the expansion of profit making in the health sector and the defense of the constitutional SUS. Despite the plurality of interests, it was identified a political alignment between the forums regarding the defense of the SUS, seeking to broaden the power of the CNS in the decision-making process of health policy. This convergence reveals how compelled the CNS is, given the current situation of social security dismantling.

ABSTRACT Chronic neurological disorders generate disabilities affecting multiple aspects of life, including sexuality. Objective To describe the presence of sexual dysfunction and comorbidities in a population with chronic neurological disorders. To analyze the relationship between disability and sexual dysfunction. Methods A cross-sectional case-control study was carried out. Patients with amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), Parkinson’s disease (PD), and stroke of at least one year since the onset of symptoms were included, and compared with controls with no neurological disease, matched by age and sex. Results We included 71 participants: 29 controls, with a mean age of 49.4 years, and 42 patients with a mean age of 53.8 years. Sexual dysfunction was present in 22.5% of the controls and 77.5% of the patients. A statistically significant relationship between sexual dysfunction and disability was found in the logistic regression analysis (OR = 20.38, 95%CI: 2.5 –165.86). Conclusions Disability proved to be the main variable related to the presence of sexual dysfunction. Patients with ALS had the worst rates of sexual dysfunction. Patients with MS were similar to the control group. As for the PD group, no patient had normal sexuality. Finally, in stroke patients, the presence of comorbidities and their treatment may have negatively influenced sexuality. These findings showed that patients with chronic neurological diseases have sexual dysfunction and underscore the need for neurologists to know and address this problem.

RESUMO Las enfermedades neurológicas crónicas generan discapacidad afectando múltiples aspectos de la vida, incluida la sexual. Objetivo Describir en una población con enfermedades neurológicas crónicas la presencia de disfunción sexual y posibles comorbilidades acompañantes. Analizar la relación entre discapacidad y disfunción sexual. Métodos Se realizó un estudio transversal de tipo casos y controles. Se incluyeron pacientes con Esclerosis Lateral Amiotrófica (ELA), Esclerosis Múltiple (EM), enfermedad de Parkinson (EP) y secuelados por enfermedad cerebrovascular (sACV) de al menos un año de evolución, controlando con sujetos sin enfermedad neurológica pareados por edad y sexo. Resultados Se incluyeron 71 sujetos: 29 controles, con una edad media 49,4 años y 42 casos con una edad media de 53,8 años. Presentaron disfunción sexual el 22,5% de los controles y el 77,5% de los casos. En el análisis por regresión logística se encontró una relación estadísticamente significativamente entre disfunción sexual y discapacidad. (OR = 20.38, IC95%: 2.5–165.86). Conclusiones La discapacidad demostró ser la principal variable relacionada con la presencia de disfunción sexual. Los enfermos con ELA fueron los que peores índices de disfunción sexual presentaron. Los pacientes con EM se comportaron de forma similar al grupo control. En cuanto al grupo de EP todos los pacientes tuvieron algún trastorno en su sexualidad. Por último, en sACV la presencia de comorbilidades y su tratamiento podrían influir negativamente en la sexualidad. Estos hallazgos evidencian que la disfunción sexual está presente en los pacientes con enfermedades neurológicas crónicas y confirma la necesidad de conocer este problema por parte de los neurólogos.

RESUMO A Osteodistrofia Hereditária de Albrighth é uma alteração que compreende características fenotípicas de origem genética, tais como baixa estatura, obesidade e braquidactília. É uma desordem rara e está relacionada com o pseudo-hipoparatireoidismo. No âmbito da Odontologia pode estar associada à hipoplasia de esmalte e erupção tardia dos dentes. Além disto em função de problemas neurológicos estes pacientes podem impor dificuldades de comportamento no momento do atendimento. O presente estudo objetivou descrever um caso clínico de uma paciente, com o possível diagnóstico de Osteodistrofia Hereditária de Albright, apresentando sintomas e limitações ao tratamento odontológico.

ABSTRACT Albright hereditary osteodystrophy is a disorder comprising phenotypic characteristics of genetic origin, such as short stature, obesity, and brachydactyly. It is a rare disorder and is related to pseudohypoparathyroidism. Within dentistry, it may be associated with enamel hypoplasia and late eruption. Furthermore, due to neurological problems, these patients may impose behavioural difficulties during dental appointments. The present study aims to describe the case of a patient with a possible diagnosis of Albright hereditary osteodystrophy, presenting symptoms and limitations to dental management.